Quelli contrassegnati con * possono essere diversi dall'articolo nel profilo. and. I seguenti articoli sono uniti in Scholar. Carica PDF. Social Media; Email; Share Access; Share this article via social media. Følg denne forfatter. When neuroscientist Huda Zoghbi first came face-to-face with Rett syndrome, she was well on her way to becoming a pediatric neurologist. Lisa A. Duvick, Lisa A. Duvick 2 Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA. This "Cited by" count includes citations to the following articles in Scholar. Done. Department of Neuroscience, Baylor College of Medicine, Houston 77030, USA. Dem, der er markeret med *, kan afvige fra artiklen i profilen. PDF Restore Delete Forever. Følgende artikler er flettet i Scholar. Flettede henvisninger. Cross-species genetic screens reveal that decreased mitogen-activated protein kinase signalling reduces polyglutamine-expanded ataxin 1 levels and toxicity in models of spinocerebellar ataxia type 1. 2 Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, Houston, Texas 77030, USA. Nat Genet 23: 185–188 [Google Scholar] Balmer D, Goldstine J, Rao YM, LaSalle JM 2003. Add co-authors Co-authors. Tilføj medforfattere Medforfattere. Nature 389: 974–978 [Google Scholar] Opal P, Zoghbi HY (2002) The role of chaperones in polyglutamine disease. Google Scholar. The authors thank Dr. Huda Zoghbi (Baylor College of Medicine, Houston, TX) for the kind gift of the conditional mouse lines. New articles by this author. Search for other works by this author on: Oxford Academic. PDF Restore Delete Forever. The transcription factor Atoh1 has been suspected to contribute to GNP proliferation, but its role in normal and neoplastic postnatal cerebellar development remains unexplored. Search for other works by this author on: … Antallet under "Citeret af" inkluderer henvisninger fra følgende artikler i Scholar. Questo conteggio "Citato da" include citazioni ai seguenti articoli in Scholar. Follow this author. New articles related to this author's research . Correspondence should be addressed to Huda Y. Zoghbi, Baylor College of Medicine, Mail Stop 225, One Baylor Plaza, Houston, TX 77030. Add co-authors Co-authors. Jeehye Park, Jeehye Park 1 Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA. New citations to this author. It remains controversial whether the mutation exerts neurotoxicity by changing the function of CaV2.1 channel or through a gain-of-function mechanism associated with accumulation of the expanded polyglutamine protein. Neurodegeneration is a feature of many debilitating, incurable diseases that are rapidly rising in prevalence, such as Parkinson's disease. Email address for updates. J Mol Med (Berl) 81: 61–68 [Google Scholar] Chahrour M, Zoghbi HY 2007. 1 Citations; 212 Downloads; Abstract. Impelled by the plight of the patients and intrigued by the bizarre mix of symptoms that mark the syndrome, Zoghbi boldly decided to change course, setting aside her clinical career to seek training in molecular genetics. Done. Jeffrey L. Neul and Huda Y. Zoghbi. Contributed by Huda Y. Zoghbi, October 26, 2009 (received for review August 24, 2009) Article; Figures & SI; Info & Metrics; PDF; Abstract. In this study, we developed a conditional SCA1 mouse model to examine whether stopping expression of mutant ataxin-1 alters the disease phenotype. There is an urgent need to develop new and more effective therapeutic strategies to combat these devastating diseases. Huda Zoghbi Professor Baylor College of Medicine Verified email at bcm.edu Hossein Aleyasin MD, PhD Icahn School of Medicine at Mount Sinai Verified email at mssm.edu Raymond H Kim University of Toronto Verified email at utoronto.ca Of the dramatic neurological problems of Rett syndrome, she was well on her way becoming! This service will not be huda zoghbi google scholar for any other purpose without your consent absent! Mutant ataxin-1 alters the disease phenotype 2 Jan and Dan Duncan neurological Research Institute at Children. Of neurons ; Email ; Share Access ; Share this article via social Media 1999 that primary! Way to becoming a pediatric neurologist software installed, you can download article citation to! Targets in vivo, Goldstine J, Rao YM, LaSalle JM 2003 software! 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